{"meta": {"offset": 0, "limit": 20, "total": 3}, "objects": [{"id": "fk06qz3", "title": "Director, Neuroscience Research & Drug Discovery", "client_name": "vergegenomics", "description": "

Position Summary:

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Verge Genomics is seeking a motivated and highly accomplished “drug hunter,” responsible for directing, managing, and leading basic research and drug discovery efforts for neurodegenerative diseases and leading multidisciplinary project teams. This position offers the opportunity to grow and lead a drug discovery program at an emerging biotech from the ground up, while establishing important external partnerships. As a member of the early team at Verge, you will be deeply involved in key strategic decisions and in organization of the research & discovery team, and help build the foundation of a revolutionary drug development model.

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Responsibilities:

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  1. Play a key leadership role in expanding Verge’s drug discovery programs from inception to clinical candidate selection.
    2. \n
  2. Develop a neuroscience discovery group that will establish and employ innovative approaches to identify and validate small molecule therapeutics for neurodegeneration
    3. \n
  3. Work with an extensive network of CROs and academic partners for the design, analysis, and interpretation of key experimental data from target ID to clinical candidate selection. This will include helping establish the key assays by which novel biology and technology are created, and assist in transitioning these to specific pipeline drug candidates.
    4. \n
  4. Establish aggressive but achievable goals that will support the overall goals of neurodegenerative research group.
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  5. Develop and maintain collaborative relationships with key opinion leaders and academic/industry partners.
    6. \n
  6. Mentor, train and direct PhD scientists in these efforts and assure their productivity
    7. \n
  7. Provide direction and vision to set the Neuroscience portfolio strategy and lead multidisciplinary scientific groups to drive compound specific discovery programs. Reports to the Chief Executive Officer. 
    8. \n
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Requirements:

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  1. Ph.D. in Neuroscience, Physiology, Molecular Biology/Cell Biology or related fields
    2. \n
  2. Minimum 10 years of progressive industry experience in Neuroscience or Neuroscience-related areas, with significant contributions to the field as demonstrated by peer-reviewed publications and presentations at national or international meetings
    3. \n
  3. Track record of overseeing development of candidates from target identification through IND-enabling studies
    4. \n
  4. Strong record of basic or translational research on neurodegnerative disease, with broad experience across a wide variety of in vitro and in vivo methods in neuroscience discovery
    5. \n
  5. Significant experience and comfort working in an outsourced model of drug discovery, including experience establishing and managing collaborative alliances with CROs, industry partners, and academic institutions.
    6. \n
  6. Successful track record of leading large teams or multiple groups
    7. \n
  7. Proven ability to hire, coach and develop world class talent
    8. \n
  8. Excellent leadership capabilities with demonstrated skill in building, guiding and motivating effective teams and fostering productive research collaborations
    9. \n
  9. Outstanding communication skills and ability to collaborate across multidisciplinary scientific discovery settings.
    10. \n
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Preferred:

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  1. Strong and established pharmacology background in interrogating mechanisms in vitro and vivo using genetics, small molecules and proteins.
    2. \n
  2. Demonstrated contributions to R&D efforts that have led to the development of clinical candidates
    3. \n
  3. Experience in establishing a linkage between human disease and developing biomarker strategies for integration and translation into clinical development plans.
    4. \n
  4. Ability to be a self-starter and to identify and communicate priorities in the absence of complete information. 
    5. \n
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Education: Ph.D. in Neuroscience, Physiology, Molecular Biology/Cell Biology or related fields with minimum 10 years industry experience 

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Location: Must be based in the San Francisco area to work in person. Relocation available.                            

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Compensation: Compensation will be based on experience and include significant equity ownership. Full benefits & start-up perks provided.

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If interested, please submit a letter of interest and CV to careers@vergegenomics.com. 

", "location": {"city": "San Francisco", "state": "California", "country": "United States", "zipcode": "94103"}, "tags": [], "hosted_url": "https://vergegenomics.hire.trakstar.com/jobs/fk06qz3/", "allows_remote": false, "position_type": "full_time", "team": null, "close_date": null}, {"id": "fk0h4bp", "title": "Senior Scientist, Neuroscience Research & Drug Discovery", "client_name": "vergegenomics", "description": "

Position Summary:

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Verge Genomics is seeking a highly motivated individual to spearhead pre-clinical development of disease modifying treatments for neurodegenerative diseases. You will be responsible for advancing our current and emerging lead candidate pipeline through all stages of pre-clinical development, acting as a leader of multidisciplinary project teams. You will oversee important external collaborations with contract research organizations (CROs), leading academic groups, non-profits, and pharmaceutical partners. As one of the first employees at Verge, you will develop help build the foundation of a revolutionary drug development model.

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Responsibilities:

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  1. Manages and leads multiple projects evaluating efficacy of small molecules for treatment of Alzheimer’s Disease, ALS, and Parkinson’s Disease
    2. \n
  2. Identifies, engages, and manages external collaborations with CROS, leading academic groups, and patient advocacy organizations
    3. \n
  3. Generate and implement pre-clinical development plans with aggressive timelines that are well-designed, rigorous, and cost-efficient
    4. \n
  4. Maintain strong relationships with pharmaceutical partners and key opinion leaders, with emphasis on understanding their needs and adapting research strategy accordingly
    5. \n
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Requirements:

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  1. Minimum of 2-5 years of doctoral, post-doctoral or professional experience in Molecular Biology, Neuroscience, or other Life Science related field
    2. \n
  2. Experience with in vitro and in vivo models of Alzheimer’s Disease, ALS, and/or Parkinson’s Disease
    3. \n
  3. Experience establishing and managing research collaborations with CROs and academic institutions
    4. \n
  4. Excellent communication skills and ability to collaborate across multidisciplinary scientific discovery settings.
    5. \n
  5. Demonstrated organizational skills in managing multiple projects at a time
    6. \n
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Preferred:

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  1. Experience testing potential therapeutic molecules in biotech/pharmaceutical settings
    2. \n
  2. Familiarity with experimental endpoints ranging from histology to behavior
    3. \n
  3. Strong scientific background as evidenced by publications in high impact journals
    4. \n
  4. Familiarity with large-scale genomic and gene expression analyses
    5. \n
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Education: MS or PhD in Molecular Biology, Neuroscience, Biochemistry, or other related life sciences field

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Location: Must be based in the San Francisco area to work in person. Relocation available.

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Compensation: Compensation will be based on experience and include significant equity ownership. Full benefits & start-up perks provided. 

", "location": {"city": "San Francisco", "state": "California", "country": "United States", "zipcode": "94103"}, "tags": [], "hosted_url": "https://vergegenomics.hire.trakstar.com/jobs/fk0h4bp/", "allows_remote": false, "position_type": "full_time", "team": null, "close_date": null}, {"id": "fk0h4b3", "title": "Computational Biologist", "client_name": "vergegenomics", "description": "

Position Summary:

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Verge Genomics is looking for a genomics scientist to develop algorithms, statistical methods, and software to analyze large-scale gene expression and genomic datasets. You will implement these methods to identify new disease targets and mechanisms, and drugs that target these disease gene networks. As one of the first employees at Verge, you will develop cutting-edge methods that will serve as the foundation of a revolutionary drug development model.

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Responsibilities:

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  1. Develop and implement methods for integrative analysis of microarray, RNA-sequencing, and GWAS data to identify gene networks involved in disease.
    2. \n
  2. Develop and implement novel pattern-matching methods for querying drug response databases with gene expression signatures.
    3. \n
  3. Integrate gene expression, behavioral, and biochemical datasets (and potentially patient EMR and prescription records), to predict which drugs are more likely to succeed in clinical trials
    4. \n
  4. Collaborate with internal and external research scientists in big pharma, small biotech, and patient advocacy organizations on analyzing genomic data for novel target discovery and drug development.
    5. \n
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Requirements:

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  1. Minimum of 2-5 years of doctoral, post-doctoral or professional experience analyzing or interpreting large-scale genomic/genetic datasets.
    2. \n
  2. Extensive experience with R development, preferably for genetics/genomics applications.
    3. \n
  3. Experience with differential expression and gene network analyses
    4. \n
  4. Excellent communication skills and ability to collaborate across the organization.
    5. \n
  5. Strong desire to work in a high-energy, hands-on startup environment.
    6. \n
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Preferred:

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  1. Prior experience with public repositories of genetic, genomic, and drug response data (ArrayExpress, GEO, CMAP).
    2. \n
  2. Prior project experience with experimental models of neurodegenerative disease.
    3. \n
  3. Prior experience with drug discovery and/or development.
    4. \n
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Education: MS or PhD in statistics, bioinformatics, computational biology, computer science, statistical genetics, or a related field.

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Location: Must be based in the San Francisco area to work in person. Relocation available.

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Compensation: Compensation will be based on experience and include significant equity ownership. Full benefits & start-up perks provided.

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